The Extracellular Matrix in Digestive Cancer
نویسندگان
چکیده
منابع مشابه
The extracellular matrix: A dynamic niche in cancer progression
The local microenvironment, or niche, of a cancer cell plays important roles in cancer development. A major component of the niche is the extracellular matrix (ECM), a complex network of macromolecules with distinctive physical, biochemical, and biomechanical properties. Although tightly controlled during embryonic development and organ homeostasis, the ECM is commonly deregulated and becomes d...
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Tissue engineering deals with the growth and regeneration techniques of connective tissues or organs from a combination of cells and a scaffold to produce a functional organ. The engineering techniques therefore begin with an implantation of artificial materials, providing a proper environment for cells or tissues to be grown and functionalized. The scaffolds are often formulated with biodegrad...
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BACKGROUND Preoperative radiotherapy reduces local recurrence due to rectal cancer, but increases postoperative morbidity. The aim of this thesis was to study the impact of radiotherapy on extracellular matrix (ECM) remodelling enzymes and growth factors after radiotherapy and also their possible use as surrogate markers for complications. A secondary aim was to explore the use of these enzymes...
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ژورنال
عنوان ژورنال: Cancer Microenvironment
سال: 2010
ISSN: 1875-2292,1875-2284
DOI: 10.1007/s12307-010-0053-4